TATALAKASANA TERKINI HIPERTENSI PULMONER PADA ANAK
DOI:
https://doi.org/10.20527/jps.v10i2.13407Kata Kunci:
Penyakit Jantung Bawaan, Hipertensi Pulmoner, Anak, Left-to-right Shunt, VasodilatorAbstrak
Hipertensi pulmoner (HP) merupakan suatu kondisi dimana terjadi peningkatan tekanan vaskular paru yang berkaitan dengan berbagai etiologi. Pada anak, sekitar 50% HP seringkali ditemukan pada pasien dengan penyakit jantung bawaan dengan left-to-right shunt, penyakit pulmonal, gangguan perkembangan paru serta idiopatik. Insiden HP pada anak secara umum dilaporkan sebesar 4-10 kasus per 1 juta anak per tahun. Terapi koreksi secara operatif atau kateterisasi masih menjadi pilihan utama untuk koreksi HP. Namun tingkat morbiditas dan mortalitas paska koreksi dilaporkan cukup tinggi. Oleh karena itu, beberapa studi terus mengkaji dan mengembangkan pilihan terapi untuk HP. Beberapa diantaranya adalah terapi vasodilator dengan PDE-5, CCB, analog prostasiklin dan inhalasi NO. Karena etiologi yang sangat komplek dan belum banyak bukti klinis atau konsensus tentang tatalaksana HP pada anak, maka pemilihan terapi HP yang sesuai masih cukup sulit. Pada prinsipnya tujuan utama dari terapi HP adalah meningkatkan angka harapan hidup dan memfasilitasi pasien agar dapat melakukan aktivitas secara mandiri tanpa limitasi. Tujuan dari penulisan tinjauan kepustakaan ini adalah untuk membahas tentang tatalaksana terkini HP pada anak sehingga diharapkan dapat menambah pengetahuan dan referensi sebagai dasar praktis klnis tentang tatalaksana HP pada anak.Referensi
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