Larvacide Activity of Bungur Plants (Lagerstroemia loudonii T. & B.)

Authors

DOI:

https://doi.org/10.20527/jps.v9i1.9982

Keywords:

Larvacide, Bungur (Lagerstroemia loudonii T. & B.), Aedes aegypti, LC50

Abstract

The prevalence of DHF, especially in Indonesia, is still high. Dengue Hemorrhagic Fever (DHF) is a disease transmitted by the Aedes aegypti species mosquito vector. Therefore, reducing the incidence of DHF requires efforts to break the chain of transmission by inhibiting the growth of the Aedes aegypti mosquito vector. One of the plants that can inhibit the growth of A. aegypti mosquito larvae is the bungur plant. This study aimed to determine the larvicidal activity of ethanol extract of leaves, bark, stems, and fruit of bungur (Lagerstroemia loudonii T. & B.) against A. aegypti larvae. Extraction process used maceration method with 96% ethanol solvent. Phytochemical screening results showed that the ethanol extract of bungur leaves and fruit contains alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids as well as steroids and triterpenoids, whereas in the ethanol extract bungur bark and stems contains alkaloids, flavonoids, saponins, quinones, tannins, polyphenols, monoterpenoids, and sesquiterpenoids. LC50 values of ethanol extract of leaves, bark, stems, and bungur fruit were 374.64 ± 11.88 µg/mL, 396.70 ± 3.99 µg/mL, 425.80 ± 8.15 µg/mL, and 312.54 ± 2.24 µg/mL, consecutively. The results showed that the ethanol extract of the leaves, bark, stems, and fruit of bungur could inhibit the growth of A. aegypti larvae. Ethanol extract of bungur fruit has the best larvicidal activity compared to other test extracts.

References

Achmadi UF, Sudjana P, Sukowati S, Wahyono TYM, Haryanto B, et al. 2010. Dengue Hemorrhagic Fever. Epidemiology Window Bulletin. Jakarta: Indonesian Ministry of Health.

Anonymous.2000. General Standard Parameters of Medicinal Plant Extracts. Jakarta; Directorate General of Drug and Food Control, Directorate of Traditional Drug Control. 9-11, 31.

Cania, E., & Setyanimgrum, E. 2013. Effectiveness Test of Larvacide Extract of Legundi Leaves (Vitex trifolia) Against Aedes aegypti Larvae. Medical Journal of Lampung University, 52 (4), 52–60. Retrieved from http://jukeunila.com/MAJORITY/ Volume 2 No.4 / 62-116-1-SM.pdf Health.

Cheeke, R. P. 2004. Saponins: Surprising Benefits Of Desert Plants, 621–632.

Cronquist, A. An Integrated System of Classification of Flowering Plants. New York: Columbia University Press.

Daniel. 2008. When Adult Larvae and Mosquitoes Are Immune to Insecticides. Farmacia Vol.7 No.7.

Dalimartha, S. 1982. Atlas of Medicinal Herbs Indonesia, Volume 2. Trubus Agriwidya, pp. 41-44. 2003.

Dinata, A. 2008. Overcome DHF larvae with Jengkol bark. Inside Magazine, III (2).

Dina P, Eka AP, Meta S. 2015. Activity Test Larvacide Ethyl Acetate Extract Herba Anting-Earrings (Alcalypha indica L.) Against Aedes aegypti Mosquito Larvae. Farmagazine Vol.2 No.1,

Harmita and Radji. 2008. M. Biological Analysis. Jakarta: EGC.

Hui Huanng G, Zhan Q, Li Li J, Chen C, Dou Huang D, Shen Chen W, Na Sun L. 2013. Constituent chemical from leaves of Lagerstroemia speciosa L. Biochemicall Systematics and Ecology 51.109-112. China.

Hutapea, D. J. R., & et al.1993. Indonesian Medicinal Plant Inventory Volume III. Jakarta: Indonesian Ministry of Health. Health Research and Development Agency.

Judy, Day PS, Stogsdill WW, Judy SJ, Naguib AMY and Passwater R. 2003. Antidiabetic activity of a standardized extract (GlucosolTM) from Lagerstroemia speciosa leaves in Type II diabetics A dose-dependent study. Journal of Ethnopharmacology 87.115-117.

Junaid S, Rakesh KN, Dileep N, Poornima G, Kekuda TRP and Mukunda S.2012. Total Phenolic Content and Antioxidant Activity of Seed Extract of Lagerstroemia Speciosa L. Chemical Science Transaction, 2 (1), 75-80.

Meyer, B. N.1982. Brine Shrimp: A Convenient General Bioassay for Active Plant Constituents. Journal of Medical Plant Research, 45. https://doi.org/10.1055/s-2007-971236.

Nasrin F, Ahmad S and Kamrunnahar.2012. Evaluation of antimicrobial, antioxidant and cytotoxic activities for methanolic extracts of leaves and barks. Journal of Applied Pharmaceutical Science Vol. 2 (10), pp. 142-147.

Ndione, R., Faye, O., Ndiaye, M., Dieye, A., & Afoutou, J. 2007. Toxic effect of nimba product (Azadirachta indica A. Juss) on Aedes aegypti Linnaeus 1762 larvae. In African Journal of Biotechnology, 6.

Pratiwi, D., Prahastiwi, E. A., & Safitri, M. 2015. Larvacide Activity Test Ethyl Acetate Extract Earring Herb (Alcalypha indica. L) Against Aedes aegypti Mosquito Larvae, 2 (1), 16-23.

Redha Abdi.2010. Flavonoids: Structure, Antioxidant Properties and Their Role in Biological Systems. Belian Journal, 9, 196–202.

Ridha, M. R., & Nisa, K. 2011. Aedes aegypti larvae have been tolerant of Temepos in Banjarbaru City, South Kalimantan. Jurnal Vektora, III (2).

Saleh Ibnu Mohammad. 2016. Activity of α-glucosidase enzyme inhibitors Bungur skin, stem extract and fraction (Lagerstroemia loudonii T. & B.) In vitro. Essay.UNJANI.

Sirimethawong K, Sriwattanawaruntoo C, Udeye V, and Boonphong S. 2013. Waxes and Triterpene Acid from Lagerstroemia loudonii fruit. Naresuan University Science Journal. 10 (2): 33-43.

Torres, R. C., Garbo, A. G., & Walde, R. Z. M. L. 2014. Larvicidal activity of Persea americana Mill. against Aedes aegypti. Asian Pacific Journal of Tropical Medicine, 7 (S1), S167-S170.

Wahyu WU, Aktsar RA, Abd. Malik.2015. Activity Test of Jarak Leaf Extract (Ricinus communis L.) Against Aedes aegypti Mosquito Larvae. Indonesian Fitofarmaka Journal Vol. 3.

WHO.2005. Guidlines For Laboratory And Field Testing Of Mosquito Larvacides.7-11.

Yunita, E. A., Suprapti, N. H., & Hidayat, J. W.2009. Effect of Eupatorium riparium on the Mortality and Development of Aedes aegypti Larvae. Bioma, 11 (1), 11–17.

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Published

2022-02-28

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Section

Jurnal Pharmascience